Item no. |
CD2-H525a-100ug |
Manufacturer |
ACROBiosystems
|
Amount |
100 ug |
Category |
|
Type |
Proteins Recombinant |
Format |
Powder |
Specific against |
Human |
Host |
HEK293 |
Conjugate/Tag |
Unconjugated, Fc |
Purity |
95% |
Citations |
(1) Zhao Y., et al., 2017 ,Immunogenetics. (2) Hersh C., et al., 2014, Immunotherapy. 6(3):249-59. (3) Zinzani PL., et al., 2012, Leuk Lymphoma. 53(5):789-9 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
CDW52,HE5,CD52,CAMPATH-1 antigen |
Available |
|
Manufacturers Category |
Protein / Other Recombinant Proteins |
Description |
Human CD52, Fc Tag (CD2-H525a) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ser 36 (Accession # P31358-1). |
Molecule |
CD52 |
Exp Region |
Gly 25 - Ser 36 |
Storage |
-20℃ |
Shipping |
RT |
Stability |
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution.
For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
Molecular Weight |
27.9 kDa |
Characteristics |
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 27.9 kDa. The protein migrates as 38-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin |
1.0 EU per μg |
Buffer |
Tris with Glycine, Arginine and NaCl, pH7.5 |
Background |
CAMPATH-1 antigen, also known as cluster of differentiation 52 (CD52), is a glycoprotein that in humans is encoded by the CD52 gene.It is widely expressed on the cell surface of immune cells, such as mature lymphocytes, natural killer cells (NK), eosinophils, neutrophils, monocytes/macrophages, and dendritic cells (DCs).ligation of cell surface CD52 molecules may offer costimulatory signals for T-cell activation and proliferation. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.