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Recombinant Human Desert hedgehog protein (DHH), partial (Active)

Recombinant Human Desert hedgehog protein (DHH), partial (Active)

Item no.	BM-RPC26760-100ug
Manufacturer	Biomatik
Amount	100ug
Category	Oncology By Cell Type Blastoma Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	DHH,
Similar products	DHH
Available
Gene Name	DHH
Alternative Names	DHH,
Uniprot	O43323
Source	E.coli
Expression Region	24-198aa
AA Sequence	II+GPGRGPVG RRRYARKQLV PLLYKQFVPG V PERTLGASG PAEGRVARGS ERFRDLVPNY NPD IIFKDEE NSGADRLMTE RCKERVNALA IAVMN MWPGV RLRVTEGWDE DGHHAQDSLH YEGRALD ITT SDRDRNKYGL LARLAVEAGF DWVYYESRN H VHVSVKADNS LAVRAGG
Sequence Info	Partial
Tag Info	Tag-Free
Theoretical MW	19.9 kDa
Purity	>96% as determined by SDS-PAGE and HPLC.
Storage Buffer	Lyophilized from a 0.2 um filtered 10mM PB, pH 6.0, 300mM NaCl
Endotoxin Level	Less than 1.0 EU/ug as determined by LAL method.
Biological Activity	The ED50 as determined by its ability to induce alkaline phosphatase production by C3H10T1/2(CCL-226) cells is 15-45 ug/ml.
Shipping Condition	Ice packs
Storage	Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles.
Expiry Date	1 year
Restriction	For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance	Intercellular signal essential for a variety of patterning events during development. May function as a spermatocyte survival factor in the testes. Essential for testes development.
Function	Intercellular signal essential for a variety of patterning events during development. May function as a spermatocyte survival factor in the testes. Essential for testes development.
Involvement in disease	Partial gonadal dysgenesis with minifascicular neuropathy 46, XY (PGD); 46, XY sex reversal 7 (SRXY7)
Subcellular location	Desert hedgehog protein N-product: Cell membrane, Lipid-anchor, Extracellular side, Note=The N-terminal peptide remains associated with the cell surface, SUBCELLULAR LOCATION: Desert hedgehog protein C-product: Secreted, extracellular space
Protein Families	Hedgehog family
Paythway	Hedgehogsignalingpathway

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 8/30/2024