Item no. |
BM-RPC26746-1mg |
Manufacturer |
Biomatik
|
Amount |
1mg |
Category |
|
Type |
Proteins Recombinant |
Specific against |
Human |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
PAI-2, Placental plasminogen activator inhibitor, Serpin B2, Urokinase inhibitor, |
Similar products |
PAI-2, Serpin B2, Placental plasminogen activator inhibitor, Urokinase inhibitor |
Available |
|
Gene Name |
SERPINB2, PAI2, PLANH2 |
Alternative Names |
PAI-2, Placental plasminogen activator inhibitor, Serpin B2, Urokinase inhibitor, |
Uniprot |
P05120 |
Source |
E.coli |
Expression Region |
1-415aa |
AA Sequence |
MEDLCVANTL FALNLFKHLA KASPTQNLFL SP WSISSTMA MVYMGSRGST EDQMAKVLQF NEVG ANAVTP MTPENFTSCG FMQQIQKGSY PDAILQ AQAA DKIHSSFRSL SSAINASTGN YLLESVNK LF GEKSASFREE YIRLCQKYYS SEPQAVDFLE CAEEARKKIN SWVKTQTKGK IPNLLPEGSV D GDTRMVLVN AVYFKGKWKT PFEKKLNGLY PFR VNSAQRT PVQMMYLREK LNIGYIEDLK AQILE LPYAG DVSMFLLLPD EIADVSTGLE LLESEIT YDK LNKWTSKDKM AEDEVEVYIP QFKLEEHYE L RSILRSMGME DAFNKGRANF SGMSERNDLF LSEVFHQAMV DVNEEGTEAA AGTGGVMTGR TG HGGPQFVA DHPFLFLIMH KITNCILFFG RFSS |
Sequence Info |
Full Length |
Tag Info |
Tag-Free |
Theoretical MW |
46.6 kDa |
Purity |
>95% as determined by SDS-PAGE and HPLC. |
Storage Buffer |
Lyophilized from a 0.2 um filtered 20 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1 mM Cysteine, with 5 % Trehalose |
Endotoxin Level |
Less than 1.0 EU/ug as determined by LAL method. |
Biological Activity |
The biologically active was determined by its inhibitory effect against single chain tPA induced cleavage of a chromogenic substrate in Imidazole Buffer at 37 CC. Half maximal inhibition against 1.0 ug/ml of single chain tPA was at a concentration of 1.0 ug/ml. |
Shipping Condition |
Ice packs |
Storage |
Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles. |
Expiry Date |
1 year |
Restriction |
For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals. |
Relevance |
Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. |
Function |
Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. |
Subcellular location |
Cytoplasm, Secreted, extracellular space |
Protein Families |
Serpin family, Ov-serpin subfamily |
Paythway |
Complementandcoagulationcascades |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.