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Recombinant Human Plasminogen activator inhibitor 2 protein (SERPINB2) (Active)

Recombinant Human Plasminogen activator inhibitor 2 protein (SERPINB2) (Active)

Item no.	BM-RPC26746-1mg
Manufacturer	Biomatik
Amount	1mg
Category	Oncology Peptides & Proteins Recombinant Proteins Cardiovascular Research Atherosclerosis By Organ Breast Cancer
Type	Proteins Recombinant
Specific against	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	PAI-2, Placental plasminogen activator inhibitor, Serpin B2, Urokinase inhibitor,
Similar products	PAI-2, Serpin B2, Placental plasminogen activator inhibitor, Urokinase inhibitor
Available
Gene Name	SERPINB2, PAI2, PLANH2
Alternative Names	PAI-2, Placental plasminogen activator inhibitor, Serpin B2, Urokinase inhibitor,
Uniprot	P05120
Source	E.coli
Expression Region	1-415aa
AA Sequence	MEDLCVANTL FALNLFKHLA KASPTQNLFL SP WSISSTMA MVYMGSRGST EDQMAKVLQF NEVG ANAVTP MTPENFTSCG FMQQIQKGSY PDAILQ AQAA DKIHSSFRSL SSAINASTGN YLLESVNK LF GEKSASFREE YIRLCQKYYS SEPQAVDFLE CAEEARKKIN SWVKTQTKGK IPNLLPEGSV D GDTRMVLVN AVYFKGKWKT PFEKKLNGLY PFR VNSAQRT PVQMMYLREK LNIGYIEDLK AQILE LPYAG DVSMFLLLPD EIADVSTGLE LLESEIT YDK LNKWTSKDKM AEDEVEVYIP QFKLEEHYE L RSILRSMGME DAFNKGRANF SGMSERNDLF LSEVFHQAMV DVNEEGTEAA AGTGGVMTGR TG HGGPQFVA DHPFLFLIMH KITNCILFFG RFSS
Sequence Info	Full Length
Tag Info	Tag-Free
Theoretical MW	46.6 kDa
Purity	>95% as determined by SDS-PAGE and HPLC.
Storage Buffer	Lyophilized from a 0.2 um filtered 20 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1 mM Cysteine, with 5 % Trehalose
Endotoxin Level	Less than 1.0 EU/ug as determined by LAL method.
Biological Activity	The biologically active was determined by its inhibitory effect against single chain tPA induced cleavage of a chromogenic substrate in Imidazole Buffer at 37 CC. Half maximal inhibition against 1.0 ug/ml of single chain tPA was at a concentration of 1.0 ug/ml.
Shipping Condition	Ice packs
Storage	Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles.
Expiry Date	1 year
Restriction	For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance	Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.
Function	Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.
Subcellular location	Cytoplasm, Secreted, extracellular space
Protein Families	Serpin family, Ov-serpin subfamily
Paythway	Complementandcoagulationcascades

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1mg

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Delivery expected until 11/1/2024

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