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Recombinant Human Parathyroid hormone protein (PTH),15N Stable Isotope Labeled (Active)

Recombinant Human Parathyroid hormone protein (PTH),15N Stable Isotope Labeled (Active)

Manufacturer	Biomatik
Category	Oncology Peptides & Proteins Recombinant Proteins By Organ Thyroid Cancer
Type	Proteins Recombinant
Specific against	Human
Amount	100ug
Item no.	BM-RPC26736-100ug
Targets	PTH
eClass 6.1	34160400
eClass 9.0	42020190
Available
Alias	PTH, Parathyrin
Gene Name	PTH
Alternative Names	PTH, Parathyrin
Uniprot	P01270
Source	E.coli
Expression Region	32-115aa
AA Sequence	SVSEIQLMHN LGKHLNSMER VEWLRKKLQD VH NFVALGAP LAPRDAGSQR PRKKEDNVLV ESHE KSLGEA DKADVNVLTK AKSQ
Sequence Info	Full Length of Mature Protein
Tag Info	Tag-Free
Theoretical MW	9.5 kDa
Purity	>97% as determined by SDS-PAGE and HPLC.
Storage Buffer	Lyophilized from a 0.2 um filtered PBS, pH 7.4
Endotoxin Level	Less than 1.0 EU/ug as determined by LAL method.
Biological Activity	The ED50 as determined by its ability to induce cAMP accumulation in murine MC3T3E1 cells is less than 50 ng/ml, corresponding to a specific activity of ? 2.0 x 104 IU/mg.
Shipping Condition	Ice packs
Storage	Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles.
Expiry Date	1 year
Restriction	For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance	PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. {ECO:0000269\|PubMed:21076856}.
Function	PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
Involvement in disease	Hypoparathyroidism, familial isolated (FIH)
Subcellular location	Secreted
Protein Families	Parathyroid hormone family

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 7/26/2024