Item no. |
BM-RPC26544-1mg |
Manufacturer |
Biomatik
|
Amount |
1mg |
Category |
|
Type |
Proteins Recombinant |
Specific against |
Equine |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Interleukin-1 beta Short name: IL-1 beta |
Similar products |
Interleukin-1 beta Short name: IL-1 beta |
Available |
|
Gene Name |
IL1B |
Alternative Names |
Interleukin-1 beta Short name: IL-1 beta |
Uniprot |
Q28386 |
Source |
E.coli |
Expression Region |
116-268aa |
AA Sequence |
AAMHSVNCRL RDIYHKSLVL SGACELQAVH LN GENTNQQV VFCMSFVQGE EETDKIPVAL GLKE KNLYLS CGMKDGKPTL QLETVDPNTY PKRKME KRFV FNKMEIKGNV EFESAMYPNW YISTSQAE KS PVFLGNTRGG RDITDFIMEI TSA |
Sequence Info |
Full Length of Mature Protein |
Tag Info |
Tag-Free |
Theoretical MW |
17.3 kDa |
Purity |
>95% as determined by SDS-PAGE and HPLC. |
Storage Buffer |
Lyophilized from a 0.2 um filtered PBS, pH 7.4, 0.1 % Tween-80 |
Endotoxin Level |
Less than 1.0 EU/ug as determined by LAL method. |
Biological Activity |
The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 20 pg/ml, corresponding to a specific activity of ? 5.0 x 107 IU/mg. |
Shipping Condition |
Ice packs |
Storage |
Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles. |
Expiry Date |
1 year |
Restriction |
For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals. |
Relevance |
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. |
Function |
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. |
Subcellular location |
Cytoplasm, cytosol, Lysosome, Secreted, exosome, Cytoplasmic vesicle, autophagosome, Secreted |
Protein Families |
IL-1 family |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.