Item no. |
BM-RPC26121-1mg |
Manufacturer |
Biomatik
|
Amount |
1mg |
Category |
|
Type |
Proteins Recombinant |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Available |
|
Gene Name |
CHRNA1 |
Uniprot |
P02710 |
Source |
Yeast |
Expression Region |
25-234aa |
AA Sequence |
SEHETRLVANLLENYNKVIRPVEHHTHFVDITVGL QLIQLISVDEVNQIVETNVRLRQQWIDVRLRWNPA DYGGIKKIRLPSDDVWLPDLVLYNNADGDFAIVHM TKLLLDYTGKIMWTPPAIFKSYCEIIVTHFPFDQQ NCTMKLGIWTYDGTKVSISPESDRPDLSTFMESGE WVMKDYRGWKHWVYYTCCPDTPYLDITYHFIMQRI |
Sequence Info |
Partial |
Tag Info |
N-terminal 6xHis-sumostar-tagged |
Theoretical MW |
37.9 kDa |
Purity |
>85% as determined by SDS-PAGE. |
Storage Buffer |
Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
Endotoxin Level |
Not tested |
Biological Activity |
Not tested |
Shipping Condition |
Ice packs |
Storage |
Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles. |
Expiry Date |
1 year |
Restriction |
For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals. |
Relevance |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
Function |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
Subcellular location |
Cell junction, synapse, postsynaptic cell membrane, Multi-pass membrane protein, Cell membrane, Multi-pass membrane protein |
Protein Families |
Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) subfamily, Alpha-1/CHRNA1 sub-subfamily |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.