Comparison

Recombinant Human Calmodulin (CALM1)

Item no. BM-RPC25634-1mg
Manufacturer Biomatik
Amount 1mg
Category
Type Proteins Recombinant
Specific against Human (Homo sapiens)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Available
Gene Name
CALM1
Uniprot
P0DP23
Source
E.coli
Expression Region
2-149aa
AA Sequence
ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTV MRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT MMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEE FVQMMTAK
Sequence Info
Full Length of Mature Protein
Tag Info
N-terminal 6xHis-SUMO-tagged
Theoretical MW
32.7 kDa
Purity
>85% as determined by SDS-PAGE.
Storage Buffer
Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Endotoxin Level
Not tested
Biological Activity
Not tested
Shipping Condition
Ice packs
Storage
Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles.
Expiry Date
1 year
Restriction
For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance
Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca2+. Among the enzymes to be stimulated by the calmodulin-Ca2+ complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.
Function
Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis
Involvement in disease
Ventricular tachycardia, catecholaminergic polymorphic, 4 (CPVT4); Long QT syndrome 14 (LQT14)
Subcellular location
Cytoplasm, cytoskeleton, spindle, Cytoplasm, cytoskeleton, spindle pole
Protein Families
Calmodulin family
Paythway
Excitatorysynapsepathway

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1mg
Available: In stock
available

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