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Biotinylated Human BAFFR / TNFRSF13C Protein, His,Avitag™ (MALS verified)

Biotinylated Human BAFFR / TNFRSF13C Protein, His,Avitag™ (MALS verified)

Item no.	BAR-H82E3-200ug
Manufacturer	ACROBiosystems
Amount	200 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Powder
Specific against	Human
Host	HEK293
Conjugate/Tag	Biotin, HIS, Avi
Purity	90%
Citations	(1) Thompson JS., et al.,2001, Science, 293 (5537): 2108-2111. (2) Mbrose CM., 2003, Journal of Biological Regulators and Homeostatic Agents, 16 (3): 211-213. (3) Treml LS., et al., 2006, Seminars in Immunology, 18 (5): 297-304.
ECLASS 5.1	34160400
ECLASS 6.1	34160400
ECLASS 8.0	42020190
ECLASS 9.0	42020190
ECLASS 10.0.1	32160409
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	BAFFR,TNFRSF13C,BROMIX,CD268,CVID4,prolixin,BAFF-R
Available
Manufacturers Category	Protein / MABSol® Biotin Labeled Proteins
Description	Biotinylated Human BAFFR, His, Avitag (BAR-H82E3) is expressed from human 293 cells (HEK293). It contains AA Ser 7 - Ala 71 (Accession # Q96RJ3-1).
Molecule	BAFFR
Exp Region	Ser 7 - Ala 71
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	10.1 kDa
Characteristics	This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 10.1 kDa. The protein migrates as 15-22 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Background	BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 ug

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Delivery expected until 8/9/2024

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