Item no. |
50059-M03H-2 |
Manufacturer |
Sino Biological
|
Amount |
2mg |
Category |
|
Type |
Proteins |
Specific against |
Mouse |
Host |
Human |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
AI323359, CD115, CSF-1R, Csfmr, Fim-2, Fms, M-CSF-R, M-CSFR |
Similar products |
CSF1R |
Available |
|
Molecule |
CSF1R |
Synonym |
AI323359, CD115, CSF-1R, Csfmr, Fim-2, Fms, M-CSF-R, M-CSFR |
Storage |
Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Protein Construction |
A DNA sequence encoding the mouse CSF1R (Met1-Ser511) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus. |
Expressed Host |
Human Cells |
Purity |
> 95 % as determined by SDS-PAGE |
Bio-Activity |
1. Immobilized mouse CSF1-His (Cat:51112-M08H) at 10 ug/ml (100 ul/well) can bind mouse CSF1R-Fch, The EC50 of mouse CSF1R-Fch is 0.04-0.1 ug/ml. 2. Measured by its ability to inhibit mouse CSF-induced proliferation of M?NFS?60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 0.01-0.04 ug/mL in the presence of 3 ng/ml Recombinant Human M-CSF. |
Endotoxin |
< 1.0 EU per ug of the protein as determined by the LAL method |
Predicted N Terminal |
Ala 20 |
Molecule Mass |
The recombinant mouse CSF1R/Fc is a disulfide-linked homodimer. The reduced monomer comprises 740 amino acids and has a predicted molecular mass of 83.3 kDa. The apparent molecular mass of the protein is approximately 110 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
Formulation |
Lyophilized from sterile PBS, pH 7.4 |
Accession |
CSF1R_MOUSE |
Amino acid sequence |
Met1-Ser511 |
TAG |
C-human IgG1-Fc & His |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.