Comparison

NRG1 Beta 1 Protein, Human, Recombinant (EGF Domain, Fc Tag) European Partner

Item no. 11609-H01H-2
Manufacturer Sino Biological
Amount 2 mg
Quantity options 1 mg 100 ug 2 mg 4 mg
Category
Type Proteins
Specific against Human (Homo sapiens)
Host Human
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, MSTP131, NDF, Neuregulin 1, NRG1-IT2, SMDF
Similar products NRG1
Available
Manufacturer - Category
Protein
Molecule
NRG1
Synonym
ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, MSTP131, NDF, Neuregulin 1, NRG1-IT2, SMDF
Storage
Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction
A DNA sequence encoding the EGF-like domain (Thr 176-Lys 246) of human NRG1 isoform beta1 (Q02297-6) was fused with the Fc region of human IgG1 at the N-terminus.
Expressed Host
Human Cells
Purity
> 86 % as determined by SDS-PAGE
Bio-Activity
1. Measured by its binding ability in a functional ELISA.
2. Immobilized Rhesus ErbB3 at 2 ug/mL (100 ul/well) can bind human NRG1 (isoform Beta1), The EC50 of human NRG1 (isoform Beta1) is 0.58 ug/mL.
3. Immobilized human ErbB3 at 2 ug/mL (100 ul/well) can bind human NRG1 (isoform Beta1), The EC50 of human NRG1 (isoform Beta1) is 0.43 ug/mL.
Endotoxin
< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal
Glu
Molecule Mass
The recombinant human NRG1(aa176-246?/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 331 amino acids and has a calculated molecular mass of 36.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh NRG1/Fc monomer is approximately 38 kDa.
Formulation
Lyophilized from sterile PBS, pH 7.4
Accession
Q02297-6
Amino acid sequence
Thr176-Lys246
TAG
N-human IgG1-Fc

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 2 mg
Available: In stock
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