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Human Insulin Receptor / INSR / CD220 Protein (short isoform, His Tag)

Human Insulin Receptor / INSR / CD220 Protein (short isoform, His Tag)

Item no.	11086-H08H-2
Manufacturer	Sino Biological
Amount	2mg
Category	Oncology Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite By Cell Type Blastoma Carcinoma Peptides & Proteins Recombinant Proteins Endocrine Regulation of Lipid Metabolism
Type	Proteins
Specific against	Human
Host	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD220, HHF5, Insulin Receptor
Similar products	INSR
Available
Molecule	INSR
Synonym	CD220, HHF5, Insulin Receptor
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the human INSR isoform short (NP_001073285.1) extracellular domain (Met 1-Lys 944) was expressed, fused with a polyhistidine tag at the C-terminus.
Expressed Host	Human Cells
Purity	> 95 % as determined by SDS-PAGE
Bio-Activity	Measured by its binding ability in a functional ELISA . When 1 ug/ml of biotinylated human insulin is immobilized onto a streptavidin coated plate, it can bind human insulin receptor with a linear range of 0.3-40 ug/ml .
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	His 28 & Ser 751
Molecule Mass	The secreted recombinant human INSR isoform short consists of 928 amino acids and has a predicted molecular mass of 106 (83+23) kDa. As a result of glycosylation, the apparent molecular mass of rhINSR is approximately 125-135 kDa & 40-45 kDa, corresponding to the alpha subunit and the ECD of beta subunit respectively in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	NP_001073285.1
Amino acid sequence	Met1-Lys944
TAG	C-His

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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