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Recombinant Human B-Cell Leukemia/Lymphoma His Tag

Recombinant Human B-Cell Leukemia/Lymphoma His Tag

Item no.	pro-641-10ug
Manufacturer	ProSpec
Amount	10ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins
Specific against	Human
Conjugate/Tag	His
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	Bcl-XL His
Available
Synonyms	BclXL, Bcl-X(L), Bcl-XL
Introduction	Bcl-XL is a transmembrane protein located in the mitochondrial membranes of cells that are long-lived and postmitotic, such as adult brain cells. It plays arole in the signal transduction pathway of the FAS-Ligand. Bcl-XL is an anti-apoptotic protein which is a member of the Bcl-2 family which are able to form heterodimers, and this is an significant event in the regulation of apoptosis. BCL-XL is involved in the survival of cancer cells. Bcl-xL is the leading monitor of apoptosis/active cell suicide. Bcl-xL has cell death repressor activity and therefore acts as a survival protein.
Description	Bcl-XL Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing amino acids 1-210. The Bcl-XL is expressed as His-Tag fusion protein and purified by proprietary chromatographic techniques.
Source	Escherichia Coli.
Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation	The protein contains 10mM Tris-HCL pH-8, 1mM EDTA and 250mM NaCl.
Purity	Greater than 95.0% as determined by SDS-PAGE.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Storage	Lyophilized Bcl-XL although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution Bcl-XL should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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pro-641-10ug-safety-datasheet.pdf