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Recombinant Human Casein Kinase 2 beta

Recombinant Human Casein Kinase 2 beta

Manufacturer	ProSpec
Category	Food Safety Allergenes Peptides & Proteins Recombinant Proteins
Type	Proteins
Specific against	Human
Amount	1mg
Item no.	pka-223-1mg
eClass 6.1	34160400
eClass 9.0	42020190
Available
Synonyms	Casein kinase II subunit beta, CK II beta, Phosvitin, G5a, CK2B, CK2N, CSK2B, MGC138222, MGC138224
Introduction	Casein Kinase 2 also called CK2 (also called PKCK2) is a ubiquitous Ser/Thr kinase expressed in all eukaryotes. CK2 is a tetramer composed of two catalytic kinase domains, alpha subunits, and two identical regulatory beta subunits. It has been implicated in cell cycle control, DNA repair, regulation of the circadian rhythm, and other cellular processes. The beta subunit itself does not have kinase activity, but confers stability to the CK2 alpha subunit and is involved in activity and substrate specificity.
Description	CSNK2B Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 215 amino acids and having a total molecular mass of 24.9kDa. CK2 beta is purified by proprietary chromatographic techniques.
Source	Escherichia Coli.
Physical Appearance	Sterile filtered colorless solution.
Formulation	The CSNK2B protein (1 mg/ml) contains 20mM Tris-HCl pH 8.0, 200mM NaCl, 1mM DTT, 1mM EDTA, 1uM leupeptin and 40% glycerol.
Purity	Greater than 95.0% as determinedAnalysis by SDS-PAGE.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Amino acid sequence	MSSSEEVSWI SWFCGLRGNE FFCEVDEDYI QDKFNLTGLN EQVPHYRQAL DMILDLEPDE ELEDNPNQSD LIEQAAEMLY GLIHARYILT NRGIAQMLEK YQQGDFGYCP RVYCENQPML PIGLSDIPGE AMVKLYCPKC MDVYTPKSSR HHHTDGAYFG TGFPHMLFMV HPEYRPKRPA NQFVPRLYGF KIHPMAYQLQ LQAASNFKSP VKTIR.
Storage	Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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pka-223-1mg-safety-datasheet.pdf