Item no. |
enz-371-1mg |
Manufacturer |
ProSpec
|
Amount |
1mg |
Category |
|
Type |
Enzymes |
Specific against |
Human |
ECLASS 10.1 |
32160410 |
ECLASS 11.0 |
32160410 |
UNSPSC |
12352204 |
Similar products |
ENO2 |
Available |
|
Synonyms |
Gamma-enolase, EC 4 2 1 11, 2-phospho-D-glycerate hydro-lyase, Neural enolase, Neuron-specific enolase, NSE, Enolase 2, ENO2 |
Introduction |
Neuron-specificenolase also caled NSE is a glycolytic isoenzyme which is situated in central and peripheral neurons and neuroendocrine cells. Enolase-2 is released into the CSF when neural tissue is injured. Neoplasms derived from neural or neuroendocrine tissue release Enolase-2 into the blood. Enolase-2 is a useful substance that has been detected in patients with certain tumors, such as neuroblastoma, small cell lung cancer, medullary thyroid cancer, carcinoid tumors, pancreatic endocrine tumors, and melanoma. ENO2 is 1 of the 3 enolase isoenzymes found in mammals. ENO2 isoenzyme, is found in mature neurons and cells of neuronal origin. An exchange from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. |
Description |
Human Neurone Specific Enolase produced in Human CNS having a molecular mass of 45kDa. |
Source |
Human CNS. |
Physical Appearance |
Sterile Filtered clear solution. |
Formulation |
The protein solution is in 0.01M NaH2PO4 buffer pH 7.4 containing 0.15M NaCl and 0.005M MgSO4. |
Purity |
Greater than 96.0%. |
Usage |
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
Storage |
Human NSE although stable at 4C for 1 week, should be stored at -15C. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.