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APC Anti-Mouse CD105 Antibody

APC Anti-Mouse CD105 Antibody

Item no.	RD30435F-100Testsx2
Manufacturer	Reddot Biotech
Amount	100 Testsx2
Applications	FC
Clone	MJ7/18
Specific against	Mouse
Host	Rat
Isotype	IgG2a Kappa
Conjugate/Tag	APC
Alias	Endoglin,END,Eng
Available
Storage	Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Format (Type)	Flow Cytometry Antibody
Manufactures Category	Antibodies
Background	CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β signaling by interacting with TGF-β receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases.
Buffer	PBS with 0.05% Proclin300, 1% BSA
Clonality	Monoclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 Testsx2

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Delivery expected until 9/20/2024

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