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Phospho-Dnmt1(pS714) Polyclonal Antibody

Phospho-Dnmt1(pS714) Polyclonal Antibody

Item no.	RD268053A-60uL
Manufacturer	Reddot Biotech
Amount	60 uL
Applications	IF
Specific against	Human
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Alias	ADCADN,AIM,CXXC9,DNMT,HSN1E,MCMT,m.HsaI,DNMT1
Available
Storage	Store at -20℃. Avoid freeze / thaw cycles.
Format (Type)	Phosphorylated antibody
Manufactures Category	Antibodies
Background	This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.
Concentration	1 mg/mL
Immunogen	A synthetic phosphorylated peptide around S714 of human Dnmt1 (NP_001370.1).
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method	Affinity purification
Dilution	IF 1:50-1:200

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 60 uL

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Delivery expected until 8/23/2024

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