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MCTS1 Polyclonal Antibody

MCTS1 Polyclonal Antibody

Item no.	RD268011A-60uL
Manufacturer	Reddot Biotech
Amount	60 uL
Applications	IF
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Alias	MCTS1,MCT-1,MCT1
Available
Storage	Store at -20℃. Avoid freeze / thaw cycles.
Format (Type)	Polyclonal Antibody
Manufactures Category	Antibodies
Background	MCTS1 (malignant T cell amplified sequence 1), also known as MCT1, is a 181 amino acid protein that is ubiquitously expressed and localizes to the cytoplasm of cells. MCTS1 may play a role in cell cycle regulation by decreasing cell doubling time and by shortening the duration of G1 transit time and G1/S transition. The protein level of Cdk4 and Cdk6 kinases activity and cyclin D1 is enhanced by expression of MCTS1. As a translation enhancer, MCTS1 recruits DENR and binds to the cap complex of the 5'-terminus of mRNAs, subsequently altering the mRNA translation profile. MCTS1 promotes lymphoid tumor development and contributes to the pathogenesis and progression of breast cancer. MCTS1 positively regulates phosphorylation of ERK1 and ERK2.
Concentration	1 mg/mL
Immunogen	Recombinant fusion protein of human MCTS1 (NP_054779.1).
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method	Affinity purification
Dilution	IF 1:50-1:200

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 60 uL

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Delivery expected until 9/20/2024

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