Item no. |
RD266787A-200uL |
Manufacturer |
Reddot Biotech
|
Amount |
200 uL |
Applications |
IF, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
Conjugate/Tag |
Unconjugated |
Alias |
FLNA,ABP-280,ABPX,CSBS,CVD1,FLN,FLN-A,FLN1,FMD,MNS,NHBP,OPD,OPD1,OPD2,XLVD,XMVD,filamin-A |
Available |
|
Storage |
Store at -20℃. Avoid freeze / thaw cycles. |
Format (Type) |
Polyclonal Antibody |
Manufactures Category |
Antibodies |
Background |
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene. |
Concentration |
1 mg/mL |
Immunogen |
A synthetic peptide of human FLNA (NP_001104026.1). |
Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Purification Method |
Affinity purification |
Dilution |
IHC 1:50-1:200 IF 1:50-1:200 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.