Item no. |
RD219816A-120uL |
Manufacturer |
Reddot Biotech
|
Amount |
120 uL |
Applications |
IHC, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
Conjugate/Tag |
Unconjugated |
Alias |
CLMF,CLMF p40,CLMF2,Cytotoxic lymphocyte maturation factor 40 kDa subunit,IL 12B,IL-12 subunit p40,IL-12B,IL12 p40,IL12B,IMD28,IMD29,Interleukin 12 beta chain,Interleukin 12 p40,Interleukin-12 subunit beta,NK cell stimulatory factor chain 2,NKSF,NKSF2 |
Available |
|
Storage |
Store at -20℃. Avoid freeze / thaw cycles. |
Format (Type) |
Polyclonal Antibody |
Manufactures Category |
Antibodies |
Background |
Interleukin-12 (IL-12), is a cytokine that is secreted by activated phagocytes and dendritic cells and that induces interferon-γproduction by natural-killer and T lymphocytes. IL-12 is a 75 kDa heterodimer composed of a 35 kDa subunit (IL-12A p35) and a 40 kDa subunit (IL-12B p40) that is secreted by a wide variety of antigen presenting cells (APCs), including phagocytes, B cells and Langerhans cells. IL-12B has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of IL-12B was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of IL-12B has been reported to be associated with the severity of atopic and non-atopic asthma in children. |
Concentration |
1.32 mg/mL |
Immunogen |
Synthetic peptide of human IL12B |
Buffer |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
Purification Method |
Antigen affinity purification |
Dilution |
IHC 1:40-1:200, ELISA 1:5000-1:10000 |
Clonality |
Polyclonal |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.