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Recombinant human CD16a/FCGR3A protein

Recombinant human CD16a/FCGR3A protein

Item no.	NKM-ATGP4102-500ug
Manufacturer	NKMAX
Amount	500ug
Applications	SDS-PAGE
Specific against	Human
Conjugate/Tag	His-Tag
Purity	> 95% by SDS-PAGE
Citations	Ravetch JV., et al. (1989) J Exp Med. 170:481-497.<br> Ferrara C., et al. (2011) Proc Natl Acad Sci U S A. 108:12669-12674.
NCBI	NP_001121065.1
Alias	Low affinity immunoglobulin gamma Fc region receptor III-A,low affinity immunoglobulin gamma Fc region receptor III-A isoform c, IgG Fc receptor III-A, CD16-II, CD16a antigen, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcgammaRIIIA, FcR-10, IgG Fc receptor III-2, CD16a, FCGR3A, CD16A, FCG3, FCGR3, FCGRIII, IGFR3, IMD20, CD16
Similar products	ATGP4102-10ug, ATGP4102-20ug, ATGP4102-50ug, ATGP4102-100ug, ATGP4102-250ug, ATGP4102-500ug, ATGP4102-1mg, ATGP4102-10, ATGP4102-20, ATGP4102-50, ATGP4102-100, ATGP4102-250, ATGP4102-500, ATGP4102-1, ATGP3449-10ug, ATGP3449-20ug, ATGP3449-50ug, ATGP3449-100ug, ATGP3449-250ug, ATGP3449-500ug, ATGP3449-1mg, ATGP3449-10, ATGP3449-20, ATGP3449-50, ATGP3449-100, ATGP3449-250, ATGP3449-500, ATGP3449-1
Available
Domain	18-208aa
Description	FCGR3A, also known as low affinity immunoglobulin gamma Fc region receptor III-A, is a multifunctional, low or intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is expressed on human NK cells as an integral membrane glycoprotein anchored through a transmembrane peptide. It mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Recombinant human FCGR3A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration	0.25mg/ml (determined by absorbance at 280nm)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Bioactivity Comment Only	Measured by its binding ability in a functional ELISA with Human IgG1 Fc (CAT# ATGP4094).
Manufacturers Gene Category	Immunology
Molecular Weight	22.8 kDa (200aa)
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment and Pics	Human Fc gamma RIIIA/CD16a is coated at 10 ug/ml (100 ul/well) can bind Human IgG1 Fc (CAT# ATGP4094) in a functional ELISA assay.
Bioassay Procedure	MRTEDLP KAVVFLEPQW YRVLEKDSVT LKCQGAYSPE DNSTQWFHNE SLISSQASSY FIDAATVDDS GEYRCQTNLS TLSDPVQLEV HIGWLLLQAP RWVFKEEDPI HLRCHSWKNT ALHKVTYLQN GKGRKYFHHN SDFYIPKATL KDSGSYFCRG LFGSKNVSSE TVNITITQGL AVSTISSFFP PGYQ
Expression System	Baculovirus
Predicted nterm	Ala
Manufacturers Product Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500ug

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Delivery expected until 10/4/2024

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