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Orexin B, rat, mouse

Orexin B, rat, mouse

Item no.	HY-P1349-10mg
Manufacturer	MedChem Express
CASRN	202801-92-1
Amount	10 mg
Quantity options	10mM*1 mL 10 mg 1 mg 500 ug 5 mg
Specific against	other
Purity	95.54
Citations	[1]Smart D, et al. Orexins: a new family of neuropeptides. Br J Anaesth. 1999 Nov;83(5):695-7.<br/>[2]Sakurai T, et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell. 1998 Feb 20;92(4):573-85.<br/>[3]Ziolkowska A, et al. Orexin B inhibits proliferation and stimulates specialized function of cultured rat calvarial osteoblast-like cells. Int J Mol Med. 2008;22(6):749-755.<br/>[4]Zhang G, et al. Orexin-B modulates synaptic transmission of rod bipolar cells in rat retina. Neuropharmacology. 2018;133:38-50.
Smiles	C(=O)([C@H]1N(C(CNC(=O)[C@H]2N(C([C@H](CCCNC(=N)N)N)=O)CCC2)=O)CCC1)N3[C@H](C(NCC(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC4=CN=CN4)C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCSC)C(N)=O)=O)[C@@H](C)O)=O)CC(C)C)=O)[C@H](CC)C)=O)=O)C)=O)C)=O)=O)CC(N)=O)=O)=O)CC(N)=O)=O)C)=O)CCC(N)=O)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)=O)CCC(N)=O)=O)CC(C)C)=O)=O)CCC3
Alias	Rat orexin B; Orexin B (mouse)
Available
Product Description	Orexin B, rat, mouse (Rat orexin B) is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.
StorageTemperature	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Shipping	Blue Ice
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	2936.40
Clinical Information	No Development Reported
Manufacturers Research Area	Neurological Disease; Endocrinology
Solubility	H2O : 16.67 mg/mL (ultrasonic)
Target	Orexin Receptor (OX Receptor)
Manufacturers Target	Orexin Receptor (OX Receptor)
Isoform	OX2 Receptor
Manufacturers Pathway	GPCR/G Protein; Neuronal Signaling
Manufacturers Product type	Peptides

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