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Orexin B, rat, mouse

Orexin B, rat, mouse

Item no.	HY-P1349-10mg
Manufacturer	MedChem Express
CASRN	202801-92-1
Amount	10 mg
Quantity options	10 mMx1 mL 10 mg 1 mg 500 ug 5 mg
Category	Neuroscience Neural Lineage Markers Metabolism Glucose Homeostasis Regulation of Appetite Peptides & Proteins Obesity Peptides
Type	Peptides
Specific against	other
Purity	95.54
Citations	[1]Smart D, et al. Orexins: a new family of neuropeptides. Br J Anaesth. 1999 Nov;83(5):695-7. [2]Sakurai T, et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell. 1998 Feb 20;92(4):573-85. [3]Ziolkowska A, et al. Orexin B inhibits proliferation and stimulates specialized function of cultured rat calvarial osteoblast-like cells. Int J Mol Med. 2008;22(6):749-755. [4]Zhang G, et al. Orexin-B modulates synaptic transmission of rod bipolar cells in rat retina. Neuropharmacology. 2018;133:38-50.
Smiles	C(=O)([C@H]1N(C(CNC(=O)[C@H]2N(C([C@H](CCCNC(=N)N)N)=O)CCC2)=O)CCC1)N3[C@H](C(NCC(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC4=CN=CN4)C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCSC)C(N)=O)=O)[C@@H](C)O)=O)CC(C)C)=O)[C@H](CC)C)=O)=O)C)=O)C)=O)=O)CC(N)=O)=O)=O)CC(N)=O)=O)C)=O)CCC(N)=O)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)=O)CCC(N)=O)=O)CC(C)C)=O)=O)CCC3
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Rat orexin B, Orexin B (mouse)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Peptides
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Orexin Receptor (OX Receptor)
Shipping Temperature	Blue Ice
Storage Conditions	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Molecular Weight	2936.40
Product Description	Orexin B, rat, mouse (Rat orexin B) is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.
Manufacturer - Research Area	Neurological Disease; Endocrinology
Solubility	H2O : 16.67 mg/mL (ultrasonic)
Manufacturer - Pathway	GPCR/G Protein; Neuronal Signaling
Isoform	OX2 Receptor
Clinical information	No Development Reported

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HY-P1349-10mg-safety-datasheet.pdf