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(±)-Vesamicol (hydrochloride)

(±)-Vesamicol (hydrochloride)

Item no.	HY-B1813A-50mg
Manufacturer	MedChem Express
CASRN	120447-62-3
Amount	50 mg
Quantity options	100 mg 10 mg 1ea 25 mg 50 mg 5 mg
Specific against	other
Purity	99.79
Citations	[1]S M Efange, et al. N-hydroxyalkyl derivatives of 3 beta-phenyltropane and 1-methylspiro[1H-indoline-3,4'-piperidine]: vesamicol analogues with affinity for monoamine transporters. J Med Chem. 1997 Nov 21;40(24):3905-14.<br/>[2]H Kobayashi, et al. Effects of systemic administration of 2-(4-phenyl-piperidino)-cyclohexanol (vesamicol) and an organophosphate DDVP on the cholinergic system in brain regions of rats. Brain Res Bull. 1997;43(1):17-23.
Smiles	O[C@H]1[C@H](N2CCC(C3=CC=CC=C3)CC2)CCCC1.[H]Cl
Alias	(±)-AH5183 (hydrochloride)
Available
Product Description	(±)-Vesamicol hydrochloride ((±)-AH5183 hydrochloride) is a potent vesicular acetylcholine transport inhibitor with a Ki of 2 nM. (±)-Vesamicol hydrochloride also displays high affinity for σ1 and σ2 receptors with Kis of 26 nM and 34 nM, respectively[1][2].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	295.85
Clinical Information	No Development Reported
Manufacturers Research Area	Neurological Disease
Solubility	DMSO : 20.83 mg/mL (ultrasonic; warming; heat to 60°C)
Target	Sigma Receptor
Manufacturers Target	Sigma Receptor
Isoform	Sigma 1 Receptor; Sigma 2 Receptor
Manufacturers Pathway	Neuronal Signaling
Manufacturers Product type	Reference compound

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