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N2-Isobutyryl-2'-O-methylguanosine

N2-Isobutyryl-2'-O-methylguanosine

Item no.	HY-21286-10mM
Manufacturer	MedChem Express
CASRN	63264-29-9
Amount	10mM/1mL
Specific against	other
Purity	99.97
Citations	[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Smiles	OC[C@@H]1[C@@H](O)[C@@H](OC)[C@H](N2C=NC3=C2NC(NC(C(C)C)=O)=NC3=O)O1
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Product Description	N2-Isobutyryl-2'-O-methylguanosine (N2-IBU-2'-OME-RG) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	367.36
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : 100 mg/mL (ultrasonic)
Manufacturers Target	Nucleoside Antimetabolite/Analog
Pathway	Cell Cycle/DNA Damage
Manufacturers Product type	Reference compound

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