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NLRP3-IN-37

NLRP3-IN-37

Item no.	HY-163498
Manufacturer	MedChem Express
CASRN	3033054-51-9
Amount	1 ea
Specific against	other
Citations	[1]Donna A. A, et al. WPhthalazine derivatives useful as inhibitors of nod-like receptor protein 3. Patent.WO2024064245A1.
Smiles	[H][C@@]12CCN(C)C[C@@]1(N(CC2)C3=C4N=CC=CC4=C(N=N3)C5=CC=C(C=C5O)C(F)(F)F)[H]
Available
Product Description	NLRP3-IN-37 (Compound 23) is a NLRP3 inhibitor (EC50: 5 nM). NLRP3-IN-37 can be used for NLRP3 related research, such as gout, pseudogout, CAPS, NASH fibrosis, heart failure, idiophathic pericarditis, atopic dermatitis, inflammatory bowel disease, Alzheimer's Disease, Parkinson's Disease and traumatic brain injury[1].
Shipping	Room temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	429.44
Clinical Information	No Development Reported
Manufacturers Research Area	Inflammation/Immunology; Neurological Disease
Solubility	10 mM in DMSO
Target	NOD-like Receptor (NLR)
Manufacturers Target	NOD-like Receptor (NLR)
Manufacturers Pathway	Immunology/Inflammation
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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