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NT-0249 (free base)

NT-0249 (free base)

Item no.	HY-161297A-100mg
Manufacturer	MedChem Express
Amount	100 mg
Quantity options	100 mg 10 mg 1 mg 25 mg 50 mg 5 mg
Specific against	other
Purity	95.0
Citations	[1]Thornton P, et al. Reversal of High Fat Diet-Induced Obesity, Systemic Inflammation, and Astrogliosis by the NLRP3 Inflammasome Inhibitors NT-0249 and NT-0796. J Pharmacol Exp Ther. 2024;388(3):813-826. Published 2024 Feb 15.
Smiles	CN(N=C1)C=C1N(C[C@@H]2CCCO2)S(NC(NC3=C4C(CCC4)=CC5=C3CCC5)=O)(=O)=O
Available
Product Description	NT-0249 free base is an orally active NLRP3 inhibitor. NT-0249 has anti-inflammatory activity[1].
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
MolecularWeight	459.56
Clinical Information	No Development Reported
Manufacturers Research Area	Inflammation/Immunology
Target	NOD-like Receptor (NLR)
Manufacturers Target	NOD-like Receptor (NLR)
Manufacturers Pathway	Immunology/Inflammation
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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