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Cyclopropaneacetamide-Exatecan

Cyclopropaneacetamide-Exatecan

Item no.	HY-156617-25mg
Manufacturer	MedChem Express
CASRN	2414254-36-5
Amount	25 mg
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Specific against	other
Purity	96.10
Citations	[1]Ying Hua, et al. Anti-b7h3 antibody-exatecan analog conjugate and medicinal use thereof. Patent WO2020063673A1.
Smiles	O[C@@H](C1CC1)C(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O
Available
Product Description	Cyclopropaneacetamide-Exatecan (Compound 2-A) is an ADC Cytotoxin and an Exatecan analogue. Cyclopropaneacetamide-Exatecan can be used in the synthesis of ADC such as anti-B7H3 antibody-Exatecan analogue conjugate (compound ADC-2)[1].
StorageTemperature	-20°C (Powder, sealed storage, away from moisture and light)
Shipping	Blue Ice
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	533.55
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)
Target	ADC Cytotoxin; Topoisomerase
Manufacturers Target	ADC Cytotoxin; Topoisomerase
Isoform	Camptothecins
Manufacturers Pathway	Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Manufacturers Product type	ADC Related

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Amount: 25 mg

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