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hCES2-IN-1

hCES2-IN-1

Item no.	HY-155181-100mg
Manufacturer	MedChem Express
Amount	100 mg
Specific against	other
Purity	98.18
Citations	[1]Cao Z, et al. Discovery of novel carboxylesterase 2 inhibitors for the treatment of delayed diarrhea and ulcerative colitis. Biochem Pharmacol. 2023 Sep;215:115742.
Smiles	ClC1=CC=CC2=C1N=C(C=C2)NC3=NC4=CC=CC=C4N3
Available
Product Description	hCES2-IN-1 (Compound 24) is a reversible and selective hCES2 inhibitor (IC50: 6.72 μM). hCES2-IN-1 reduces the level of hCES2 in living cells. hCES2-IN-1 is effective against Irinotecan (HY-16562)-induced delayed diarrhea and DSS-induced ulcerative colitis[1].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
MolecularWeight	294.74
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturers Target	Others
Pathway	Others
Manufacturers Product type	Reference compound

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