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Monomethyl auristatin E (GMP)

Monomethyl auristatin E (GMP)

Item no.	HY-15162G-100mg
Manufacturer	MedChem Express
CASRN	474645-27-7
Amount	100 mg
Specific against	other
Citations	[1]Okeley, et al. Intracellular Activation of SGN-35, a Potent Anti-CD30 Antibody-Drug Conjugate. Clinical Cancer Research (2010), 16(3), 888-897.
Alias	MMAE (GMP); SGD-1010 (GMP); Vedotin (GMP)
Available
Product Description	Monomethyl auristatin E (MMAE) (GMP) is Monomethyl auristatin E (HY-15162) produced by using GMP guidelines. Monomethyl auristatin E is a tubulin polymerization inhibitor[1].
Shipping	Room temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	717.98
Clinical_Information	Phase 4
Manufacturers Research_Area	Cancer
Solubility	10 mM in DMSO
Manufacturers Target	ADC Cytotoxin; Apoptosis; Microtubule/Tubulin
Pathway	Antibody-drug Conjugate/ADC Related; Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton
Manufacturers Product type	GMP Small Molecules

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