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P2X7 receptor antagonist-2

P2X7 receptor antagonist-2

Item no.	HY-150059-5mg
Manufacturer	MedChem Express
CASRN	851269-75-5
Amount	5 mg
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Specific against	other
Purity	99.21
Citations	[1]Steadman JGA, et, al. 5-oxo-3-pyrrolidinecarboxamide derivatives as p2x7 modulators. WO2009077559A2
Smiles	ClC1=CC(Cl)=C(CNC(C2CN(C(C2)=O)CC3=CC=CC=C3)=O)C=C1
Available
Product Description	P2X7 receptor antagonist-2 is a potent P2X7 receptor antagonist with a pIC50 value of 6.5-7.5. P2X7 receptor antagonist-2 has efficacy of combating neuroinflammation[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	377.26
Clinical Information	No Development Reported
Manufacturers Research Area	Inflammation/Immunology; Neurological Disease
Solubility	DMSO : 100 mg/mL (ultrasonic)
Target	P2X Receptor
Manufacturers Target	P2X Receptor
Isoform	P2X7 Receptor
Manufacturers Pathway	Membrane Transporter/Ion Channel
Manufacturers Product type	Reference compound

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