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TCO-PEG8-NHS ester

TCO-PEG8-NHS ester

Item no.	HY-141169-5mg
Manufacturer	MedChem Express
CASRN	2353409-95-5
Amount	5 mg
Quantity options	100mg 10 mg 25 mg 50mg 5 mg
Specific against	other
Purity	95.0
Citations	[1]Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.
Smiles	O=C(OC1CC/C=C\CCC1)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O
Available
Product Description	TCO-PEG8-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. TCO-PEG8-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	690.78
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	10 mM in DMSO
Target	PROTAC Linkers
Manufacturers Target	PROTAC Linkers
Isoform	PEG Linkers
Manufacturers Pathway	PROTAC
Manufacturers Product type	Reference compound

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