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Azido-PEG8-hydrazide

Azido-PEG8-hydrazide

Item no.	HY-140815-5mg
Manufacturer	MedChem Express
CASRN	2353410-11-2
Amount	5 mg
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Specific against	other
Citations	[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Smiles	O=C(NN)CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
Available
Product Description	Azido-PEG8-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG8-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
StorageTemperature	-20°C (Powder, sealed storage, away from moisture)
Shipping	Blue Ice
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	481.54
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	10 mM in DMSO
Target	PROTAC Linkers
Manufacturers Target	PROTAC Linkers
Isoform	PEG Linkers
Manufacturers Pathway	PROTAC
Manufacturers Product type	Reference compound

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