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17(R)-Resolvin D1

17(R)-Resolvin D1

Item no.	HY-125527A-25ug
Manufacturer	MedChem Express
CASRN	528583-91-7
Amount	25 ug
Quantity options	1 ea 100 ug 10 ug 25 ug 50 ug
Specific against	other
Citations	[1]Sun YP, et al., Resolvin D1 and its aspirin-triggered 17R epimer. Stereochemical assignments, anti-inflammatory properties, and enzymatic inactivation. J Biol Chem. 2007 Mar 30;282(13):9323-9334.<br/>[2]Bang S, et al., 17(R)-resolvin D1 specifically inhibits transient receptor potential ion channel vanilloid 3 leading to peripheral antinociception. Br J Pharmacol. 2012 Feb;165(3):683-92.
Smiles	CC/C=C\C[C@@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)C/C=C\CCC(O)=O
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Product Description	17R-Resolvin D1 (17R-RvD1; AT-RvD1) is an aspirin-triggered epimer of Resolvin D1, which exhibits anti-inflammatory activity in mice and human PMNs cells[1]. 17R-Resolvin D1 specificially inhibits TRPV3 with an IC50 of 398 nM and exhibits peripheral anti-nociceptive efficacy[2].
Shipping	Room temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	376.49
Clinical Information	No Development Reported
Manufacturers Research Area	Inflammation/Immunology
Solubility	10 mM in DMSO
Target	TRP Channel
Manufacturers Target	TRP Channel
Isoform	TRPV
Manufacturers Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling
Manufacturers Product type	Reference compound

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Amount: 25 ug

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