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SPDB-DM4

SPDB-DM4

Item no.	HY-12460-50mg
Manufacturer	MedChem Express
CASRN	1626359-62-3
Amount	50 mg
Quantity options	10mM*1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Specific against	other
Purity	99.91
Dry ice	Yes
Citations	[1]Puja Sapra, et al. Investigational antibody drug conjugates for solid tumors. Expert Opin Investig Drugs. 2011 Aug;20(8):1131-49.
Smiles	C[C@]1([C@H](CC(N(C(C=C2C=C3OC)=C3Cl)C)=O)OC([C@H](C)N(C)C(CCC(C)(C)SSCCCC(ON(C4=O)C(CC4)=O)=O)=O)=O)[C@H]([C@@H]([C@](OC5=O)([H])C[C@]([C@](/C=C/C=C(C)/C2)([H])OC)(N5)O)C)O1
Available
Product Description	SPDB-DM4 is a agent-linker conjugate for ADC by using the maytansinebased payload (DM4, a tubulin inhibitor) via a SPDB linker, exhibiting potent anti-tumor activity.
StorageTemperature	-80°C, protect from light, stored under nitrogen
Shipping	Dry Ice
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	995.59
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 100 mg/mL (ultrasonic)
Target	Drug-Linker Conjugates for ADC
Manufacturers Target	Drug-Linker Conjugates for ADC
Isoform	Maytansinoids
Manufacturers Pathway	Antibody-drug Conjugate/ADC Related
Manufacturers Product type	ADC Related

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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