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FRM-024

FRM-024

Item no.	HY-115726-5mg
Manufacturer	MedChem Express
CASRN	2085780-87-4
Amount	5 mg
Quantity options	100 mg 10 mg 1 ea 1 mg 25 mg 5 mg
Specific against	other
Citations	[1]Bursavich MG, et al. Discovery of the Oxadiazine FRM-024: A Potent CNS-Penetrant Gamma Secretase Modulator. J Med Chem. 2021 Oct 14;64(19):14426-14447.
Smiles	CC1=CN(C2=C(OC)N=C(C3=NO[C@@H](C4CC4)[C@@H](C5=CC=C(Cl)C=C5)N3)C=C2)C=N1
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Product Description	FRM-024 is a potent CNS-penetrant gamma secretase modulator for familial Alzheimer’s disease.
Shipping	Room temperature
Manufacturers Applications	Neuroscience-Neurodegeneration
MolecularWeight	423.90
Clinical Information	No Development Reported
Manufacturers Research Area	Neurological Disease
Solubility	10 mM in DMSO
Target	γ-secretase
Manufacturers Target	γ-secretase
Manufacturers Pathway	Neuronal Signaling; Stem Cell/Wnt
Manufacturers Product type	Reference compound

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