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Arfolitixorin (sulfate)

Arfolitixorin (sulfate)

Item no.	HY-109051C
Manufacturer	MedChem Express
CASRN	149930-93-8
Amount	1 ea
Specific against	other
Citations	[1]Carlsson G, et al. A phase I/II study of arfolitixorin and 5-fluorouracil in combination with oxaliplatin (plus or minus bevacizumab) or irinotecan in metastatic colorectal cancer. ESMO Open. 2022 Oct;7(5):100589.
Smiles	O=C(NC(N)=N1)C2=C1NC[C@@]3([H])N2CN(C4=CC=C(C(N[C@H](C(O)=O)CCC(O)=O)=O)C=C4)C3.O=S(O)(O)=O
Available
Product Description	Arfolitixorin sulfate is a potent 5-Fluorouracil (5-FU) moderator. Arfolitixorin sulfate is an immediately active form of Folate, [6R]-5, 10-methylenetetrahydrofolate ([6R]-MTHF). Arfolitixorin sulfate is potent for the research of metastatic colorectal cancer[1].
Shipping	Room temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	555.52
Clinical Information	Phase 3
Manufacturers Research Area	Cancer
Solubility	10 mM in DMSO
Target	Endogenous Metabolite
Manufacturers Target	Endogenous Metabolite
Manufacturers Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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