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(Rac)-WAY-161503

(Rac)-WAY-161503

Item no.	HY-103138A-1mg
Manufacturer	MedChem Express
CASRN	75704-24-4
Amount	1 mg
Quantity options	10mM/1mL 10 mg 1 mg 5 mg
Specific against	other
Purity	99.0
Citations	[1]Halberstadt AL, et al. 5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice. Neuropsychopharmacology. 2009 Jul;34(8):1958-67.<br/>[2]Welmaker GS, et al. Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines. Bioorg Med Chem Lett. 2000 Sep 4;10(17):1991-4.
Smiles	O=C1C(CNCC2)N2C3=C(C=C(Cl)C(Cl)=C3)N1
Available
Product Description	(Rac)-WAY-161503 is a potent, selective, highly affinity 5-HT2C receptor agonist with a Ki of 4 nM and an EC50 of 12 nM. (Rac)-WAY-161503 displays higher affinity for 5-HT2C than 5-HT2A and 5-HT2B receptors. (Rac)-WAY-161503 has anti-obesity and antidepressant effects[1][2].
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
Manufacturers Applications	Metabolism-protein/nucleotide metabolism
MolecularWeight	272.13
Clinical Information	No Development Reported
Manufacturers Research Area	Metabolic Disease; Neurological Disease
Solubility	DMSO : 100 mg/mL (ultrasonic)
Target	5-HT Receptor
Manufacturers Target	5-HT Receptor
Isoform	5-HT2 Receptor
Manufacturers Pathway	GPCR/G Protein; Neuronal Signaling
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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