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PGRN Progranulin Human Recombinant Protein

PGRN Progranulin Human Recombinant Protein

Item no.	BOS-PROTP28799-100ug
Manufacturer	Boster
Amount	100ug
Format	Lyophilized Powder
Specific against	Human
Dry ice	Yes
Alias	GRN; PGRN; granulin; Acrogranin; propithelin; PC cell derived growth Factor; GEP; GP88; PEPI; PCDGF
Available
Manufacturers Product Category	Recombinant Proteins
Short Description	Progranulin Human Recombinant produced in HEK is a single, glycosylated, polypeptide chain containing 1-593 amino acids and having a molecular mass of 74kDa. The Progranulin is purified by standard chromatographic techniques.
Description	Progranulin Human Recombinant produced in HEK is a single, glycosylated, polypeptide chain containing 1-593 amino acids and having a molecular mass of 74kDa. The Progranulin is purified by standard chromatographic techniques.
Gene Name	GRN
Contents	The protein contains 1xPBS.
Bioactivity/Biological Activity	Activates phospho-ERK1/2 in neuronal mouse P19 cells and regulates food intake and body weight.
Purification	Greater than 98.0% as determined by SDS-PAGE.
Storage	Lyophilized Progranulin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution PGRN should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Reconstitution	It is recommended to reconstitute the lyophilized Progranulin in sterile 18MΩ-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Gene Full Name	Granulins
Protein Function	Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling.
Subcellular Localization	Secreted.
Tissue Specificity	In myelogenous leukemic cell lines of promonocytic, promyelocytic, and proerythroid lineage, in fibroblasts, and very strongly in epithelial cell lines. Present in inflammatory cells and bone marrow. Highest levels in kidney.
Format Information	Sterile Filtered White lyophilized (freeze-dried) powder.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 10/4/2024

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