Item no. |
BOS-M02431-1-30ul |
Manufacturer |
Boster
|
Amount |
30ul |
Format |
Liquid |
Applications |
WB, FC, IHC |
Clone |
HHO-25 |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
Alias |
14-3-3 protein beta/alpha;Protein 1054;Protein kinase C inhibitor protein 1;KCIP-1;14-3-3 protein beta/alpha, N-terminally processed;YWHAB; |
Available |
|
Manufacturers Product Category |
Primary Antibodies, Rabbit Monoclonal Antibodies |
Manufacturers Research Category |
Adapters, Cell Type Marker, Cytoplasmic, Neural Signal Transduction, Neurology Process, Neuron Marker, Neuroscience, Signal Transduction, Signaling Pathways, Stem Cells, Synapse Marker |
Short Description |
Boster Bio Anti-14-3-3 YWHAB Rabbit Monoclonal Antibody catalog # M02431-1. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
Description |
Boster Bio Anti-14-3-3 YWHAB Rabbit Monoclonal Antibody catalog # M02431-1. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
Gene Name |
YWHAB |
Application Details |
WB 1:500-1:1000 IHC 1:50-1:200 FC 1:50 |
Clonality |
Monoclonal |
Concentration |
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
Contents |
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Immunogen |
A synthesized peptide derived from human 41701 |
Purification |
Affinity-chromatography |
Storage |
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Gene Full Name |
14-3-3 protein beta/alpha |
Molecular Weight |
28082 MW |
Protein Function |
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activatation of MAP kinases via AKAP13.. |
Subcellular Localization |
Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.