Item no. |
BOS-M00458-30ul |
Manufacturer |
Boster
|
Amount |
30ul |
Format |
Liquid |
Applications |
WB, IP |
Clone |
AAIH-9 |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
Alias |
Integrin beta-2;Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta;Complement receptor C3 subunit beta;CD18;ITGB2;CD18, MFI7; |
Available |
|
Manufacturers Product Category |
Primary Antibodies, Rabbit Monoclonal Antibodies |
Manufacturers Research Category |
Cell Adhesion, Cell Type Markers, Cytoskeleton/ECM, Hematopoietic Progenitors, Immunology, Integrins, Myeloid, Signal Transduction, Stem Cells |
Short Description |
Boster Bio Anti-CD18 ITGB2 Rabbit Monoclonal Antibody catalog # M00458. Tested in WB, IP applications. This antibody reacts with Human. |
Description |
Boster Bio Anti-CD18 ITGB2 Rabbit Monoclonal Antibody catalog # M00458. Tested in WB, IP applications. This antibody reacts with Human. |
Gene Name |
ITGB2 |
Application Details |
WB 1:500-1:2000 IP 1:50 |
Clonality |
Monoclonal |
Concentration |
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
Contents |
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Immunogen |
A synthesized peptide derived from human CD18 |
Purification |
Affinity-chromatography |
Storage |
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Gene Full Name |
Integrin beta-2 |
Molecular Weight |
84782 MW |
Protein Function |
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha- D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation.. |
Subcellular Localization |
Membrane; Single-pass type I membrane protein. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.