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Anti-p16INK4a (CDKN2A) Rabbit Monoclonal Antibody, Clone#RM267

Anti-p16INK4a (CDKN2A) Rabbit Monoclonal Antibody, Clone#RM267

Item no.	BOS-M00016-1
Manufacturer	Boster
Amount	100ul
Format	Liquid
Applications	WB, IHC
Clone	RM267
Specific against	Human
Host	Rabbit
Isotype	IgG
Alias	Cyclin-dependent kinase inhibitor 2A ;Cyclin-dependent kinase 4 inhibitor A;CDK4I;Multiple tumor suppressor 1;MTS-1;p16-INK4a;p16-INK4;p16INK4A;CDKN2A ;CDKN2, MTS1;
Available
Manufacturers Product Category	Primary Antibodies, Monoclonal Antibodies
Manufacturers Research Category	Cancer, Cancer Susceptibility, Cell Biology, Cell Cycle, Cell Cycle Inhibitors, Epigenetics and Nuclear Signaling, Oncoproteins/Suppressors, p53 Pathway, Transcription, Tumor Suppressors
Short Description	Boster Bio Anti-p16INK4a (CDKN2A) Rabbit Monoclonal Antibody, Clone#RM267 (Catalog # M00016-1). Tested in IHC, WB applications. This antibody reacts with Human.
Description	Boster Bio Anti-p16INK4a (CDKN2A) Rabbit Monoclonal Antibody, Clone#RM267 (Catalog # M00016-1). Tested in IHC, WB applications. This antibody reacts with Human.
Gene Name	CDKN2A
Clonality	Monoclonal
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Contents	50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Application Details	Immunohistochemistry (IHC): 1:500-1:1000 dilution WB: 1:500-1:1000 dilution.
Immunogen	A peptide corresponding to the C-terminus of human p16INK4a (Cyclin-dependent kinase inhibitor 2A).
Cross-reactivity	This antibody reacts to human p16INK4a (Cyclin-dependent kinase inhibitor 2A).
Purification	Protein A affinity purified from an animal origin-free culture supernatant
Storage	Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Gene Full Name	Cyclin-dependent kinase inhibitor 2A
Molecular Weight	16533 MW
Protein Function	Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
Subcellular Localization	Cytoplasm. Nucleus.
Tissue Specificity	Widely expressed but not detected in brain or skeletal muscle. Isoform 3 is pancreas-specific.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 8/30/2024

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