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Anti-DELE DELE1 Antibody

Anti-DELE DELE1 Antibody

Item no.	BOS-A31772
Manufacturer	Boster
Amount	0.1mg
Format	Liquid
Applications	WB, IF, ELISA
Specific against	Human, Rat
Host	Rabbit
Isotype	IgG
Alias	DELE, DELE, Death ligand signal enhancer
Available
Manufacturers Product Category	Primary Antibodies
Manufacturers Research Category	Apoptosis
Short Description	Boster Bio Anti-DELE DELE1 Antibody (Catalog # A31772). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Rat.
Description	Boster Bio Anti-DELE DELE1 Antibody (Catalog # A31772). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Rat.
Background	DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-α and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-α , anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors.
Gene Name	KIAA0141
Clonality	Polyclonal
Concentration	1 mg/mL
Contents	DELE Antibody is supplied in PBS containing 0.02% sodium azide.
Predicted Reactivity	Mouse
Application Details	DELE antibody can be used for detection of DELE by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL. Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Immunogen	DELE antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human DELE. The immunogen is located within the first 50 amino acids of DELE.
Purification	DELE Antibody is affinity chromatography purified via peptide column.
Storage	DELE antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Gene Full Name	KIAA0141
Molecular Weight	55920 MW
Protein Function	Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation.
Subcellular Localization	Mitochondrion
Tissue Specificity	Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.
Protein Name	KIAA0141

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1mg

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Delivery expected until 8/30/2024

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