Anti-Protein NipSnap homolog 3A NIPSNAP3A Antibody

Primary Antibodies

Boster Bio Anti-Protein NipSnap homolog 3A NIPSNAP3A Antibody (Catalog # A14892). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

The NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. NIPSNAP2, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumors. While NIPSNAP3B is highly expressed skeletal muscle, NIPSNAP3A mRNA levels are low. NIPSNAP3A protein is associated with plasma membrane and partially localized in rafts. NIPSNAP proteins have been suggested to be important in vesicular transport.

Polyclonal

NIPSNAP3A Antibody is supplied in PBS containing 0.02% sodium azide.

NIPSNAP3A antibody was raised against a 16 amino acid synthetic peptide near the center of human NIPSNAP3A. The immunogen is located within amino acids 40 - 90 of NIPSNAP3A.

NIPSNAP3A Antibody is affinity chromatography purified via peptide column.

Nipsnap homolog 3A (C. elegans)

Component of the GPI-GlcNAc transferase (GPI-GnT)
complex in the endoplasmic reticulum, a complex that catalyzes
transfer of GlcNAc from UDP-GlcNAc to an acceptor
phosphatidylinositol, the first step in the production of GPI-
anchors for cell surface proteins. May act by regulating the
catalytic subunit PIGA.

Ubiquitous. Highly expressed in liver, kidney
and muscle. Expressed at intermediate level in brain, heart,
colon, thymus, kidney, small intestine, placenta, lung, leukocytes
and spleen.