Item no. |
BOS-A13919 |
Manufacturer |
Boster
|
Amount |
0.1mg |
Format |
Liquid |
Applications |
WB, ELISA, IHC-P |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
Alias |
ZIP11, C17orf26, ZIP11, Zinc transporter ZIP11, Solute carrier family 39 member 11, ZIP-11 |
Available |
|
Manufacturers Product Category |
Primary Antibodies |
Manufacturers Research Category |
Homeostasis |
Short Description |
Boster Bio Anti-ZIP11 SLC39A11 Antibody (Catalog # A13919). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat. |
Description |
Boster Bio Anti-ZIP11 SLC39A11 Antibody (Catalog # A13919). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat. |
Background |
ZIP11, also known as Slc39A11, is a member of the broader ZIP family of multi-transmembrane domain metal ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Members of the ZIP family generally transport metal ions from the cell exterior or lumen of intracellular organelles into the cytoplasm, as opposed to the ZnT (SLC30) family of zinc transporters that serve to reduce intracellular zinc availability by promoting zinc efflux from cells or into intracellular vesicles. At least three isoforms of ZIP11 are known to exist. |
Gene Name |
SLC39A11 |
Clonality |
Polyclonal |
Concentration |
1 mg/mL |
Contents |
ZIP11 Antibody is supplied in PBS containing 0.02% sodium azide. |
Predicted Reactivity |
Bovine |
Application Details |
ZIP11 antibody can be used for detection of ZIP11 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. Antibody validated: Western Blot in mouse samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher. |
Immunogen |
ZIP11 antibody was raised against a 15 amino acid synthetic peptide near the center of the human ZIP11. The immunogen is located within amino acids 130 - 180 of ZIP11. |
Cross-reactivity |
This antibody will not cross-react with the zinc transporter ZIP10. |
Purification |
ZIP11 Antibody is affinity chromatography purified via peptide column. |
Storage |
ZIP11 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Gene Full Name |
Solute carrier family 39 (metal ion transporter), member 11 |
Molecular Weight |
35396 MW |
Protein Function |
Functions as a cellular zinc transporter. |
Subcellular Localization |
Cell membrane |
Tissue Specificity |
High expression in placenta, skeletal muscle, kidney and pancreas tissues. Absent or very faint expression in heart, brain, lung and liver. Expressed during adipogenic differentiation of mesenchymal stem cells (at protein level). |
Protein Name |
Solute carrier family 39 (metal ion transporter), member 11 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.