Item no. |
BOS-A12670 |
Manufacturer |
Boster
|
Amount |
0.1mg |
Format |
Liquid |
Applications |
WB, ELISA |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
Alias |
PP432, C8orf20, PP432, Receptor expression-enhancing protein 4 |
Available |
|
Manufacturers Product Category |
Primary Antibodies |
Manufacturers Research Category |
Signal Transduction |
Short Description |
Boster Bio Anti-REEP4 Antibody (Catalog # A12670). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. |
Description |
Boster Bio Anti-REEP4 Antibody (Catalog # A12670). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. |
Background |
Mammalian odorant receptors require accessory proteins such as RTP1 and RTP2 for functional cell surface expression. Receptor expression-enhancing protein (REEP) family members are transmembrane proteins which interact with odorant receptor proteins and may enhance the odorant receptor responses to odorants. Recently studies have shown other chemosensory receptors such as bitter taste receptors are also influenced by RTP and REEP family members. In studies in Xenopus RNAi to reduce REEP4 levels, embryos showed a slightly kinked body axis and were paralyzed. Further analysis revealed downregulated levels of several neural and muscle markers, suggesting the REEP4 may play a role in the maintenance of both the nervous system and musculature. |
Gene Name |
REEP4 |
Clonality |
Polyclonal |
Concentration |
1 mg/mL |
Contents |
REEP4 Antibody is supplied in PBS containing 0.02% sodium azide. |
Application Details |
REEP4 antibody can be used for detection of REEP4 by Western blot at 1 μg/mL. Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher. |
Immunogen |
REEP4 antibody was raised against a 17 amino acid synthetic peptide near the center of human REEP4. The immunogen is located within amino acids 160 - 210 of REEP4. |
Purification |
REEP4 Antibody is affinity chromatography purified via peptide column. |
Storage |
REEP4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Gene Full Name |
Receptor accessory protein 4 |
Molecular Weight |
29395 MW |
Protein Function |
Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis. Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes. |
Subcellular Localization |
Endoplasmic reticulum membrane |
Tissue Specificity |
Expressed in circumvallate papillae and testis. |
Protein Name |
Receptor accessory protein 4 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.