Item no. |
BOS-A12655 |
Manufacturer |
Boster
|
Amount |
0.1mg |
Format |
Liquid |
Applications |
WB, IF, ELISA, IHC-P |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
Alias |
BM-011, SFRS21, SRrp53, SRRP53, BM-011SRrp53 |
Available |
|
Manufacturers Product Category |
Primary Antibodies |
Manufacturers Research Category |
Stem Cells |
Short Description |
Boster Bio Anti-RSRC1 Antibody (Catalog # A12655). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat. |
Description |
Boster Bio Anti-RSRC1 Antibody (Catalog # A12655). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat. |
Background |
The arginine/serine-rich coiled-coil 1 protein (RSRC1) was initially identified as a non-snRNP splicing factor that has a role in both the constitutive and alternative splicing of pre-mRNA molecules. In cellular nuclear extracts immunodepleted of RSRC1, the second step of pre-mRNA splicing is blocked; recombinant RSRC1 is able to restore splicing activity. RSRC1 has also been reported to be associated with schizophrenia as well as a unique marker of bone marrow-derived stem cells that also express the cdc34 marker. |
Gene Name |
RSRC1 |
Clonality |
Polyclonal |
Concentration |
1 mg/mL |
Contents |
RSRC1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Predicted Reactivity |
Bovine |
Application Details |
RSRC1 antibody can be used for detection of RSRC1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher. |
Immunogen |
RSRC1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human RSRC1. The immunogen is located within the last 50 amino acids of RSRC1. |
Purification |
RSRC1 Antibody is affinity chromatography purified via peptide column. |
Storage |
RSRC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Gene Full Name |
Arginine/serine-rich coiled-coil 1 |
Molecular Weight |
38677 MW |
Protein Function |
Plays a role in pre-mRNA splicing. Involved in both constitutive and alternative pre-mRNA splicing. May have a role in the recognition of the 3' splice site during the second step of splicing. |
Subcellular Localization |
Nucleus. Nucleus speckle . Cytoplasm. Shuttles between the nucleus and cytoplasm.. |
Protein Name |
Arginine/serine-rich coiled-coil 1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.