Item no. |
BOS-A11860 |
Manufacturer |
Boster
|
Amount |
0.1mg |
Format |
Liquid |
Applications |
WB, IF, ELISA, IHC-P |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
Alias |
A211C6.1, LYR motif-containing protein 1 |
Available |
|
Manufacturers Product Category |
Primary Antibodies |
Manufacturers Research Category |
Obesity |
Short Description |
Boster Bio Anti-LYR motif-containing protein 1 LYRM1 Antibody (Catalog # A11860). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat. |
Description |
Boster Bio Anti-LYR motif-containing protein 1 LYRM1 Antibody (Catalog # A11860). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat. |
Background |
LYRM1 was one of many genes identified through a suppression subtractive hybridization comparing their expression in omental adipose tissue of obese patients compared to non-obese individuals. Further study confirms that both mRNA and protein levels of LYRM1 are higher in obese individuals. LYRM1 is widely expressed, with highest levels occurring in adipose and liver tissues. It is thought that LYRM1 promotes preadipocyte proliferation and can inhibit apoptosis of preadipocytes. Ectopic LYRM1 expression did not significantly affect adipogenesis, suggesting that LYRM1 can influence adipose tissue homeostasis by modulating the size of the preadipocyte pool. |
Gene Name |
LYRM1 |
Clonality |
Polyclonal |
Concentration |
1 mg/mL |
Contents |
LYRM1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Application Details |
LYRM1 antibody can be used for detection of LYRM1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher. |
Immunogen |
LYRM1 antibody was raised against a 17 amino acid synthetic peptide near the center of human LYRM1. The immunogen is located within the first 50 amino acids of LYRM1. |
Purification |
LYRM1 Antibody is affinity chromatography purified via peptide column. |
Storage |
LYRM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Gene Full Name |
LYR motif containing 1 |
Molecular Weight |
14282 MW |
Protein Function |
May promote cell proliferation and inhibition of apoptosis of preadipocytes. |
Subcellular Localization |
Nucleus |
Tissue Specificity |
High levels in adipose tissue. |
Protein Name |
LYR motif containing 1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.