Item no. |
BOS-A09987 |
Manufacturer |
Boster
|
Amount |
0.1mg |
Format |
Liquid |
Applications |
WB, ELISA |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
Alias |
NET27, ZIMP7, hZIMP7, TRAFIP20, KIAA1886, HRIHFB2007, Zinc finger MIZ domain-containing protein 2, PIAS-like protein Zimp7 |
Available |
|
Manufacturers Product Category |
Primary Antibodies |
Manufacturers Research Category |
Signal Transduction |
Short Description |
Boster Bio Anti-ZIMP7 ZMIZ2 Antibody (Catalog # A09987). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse. |
Description |
Boster Bio Anti-ZIMP7 ZMIZ2 Antibody (Catalog # A09987). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse. |
Background |
ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification. |
Gene Name |
ZMIZ2 |
Clonality |
Polyclonal |
Concentration |
1 mg/mL |
Contents |
ZIMP7 Antibody is supplied in PBS containing 0.02% sodium azide. |
Application Details |
ZIMP7 antibody can be used for detection of ZIMP7 by Western blot at 0.25 - 0.5 μg/mL. Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher. |
Immunogen |
ZIMP7 antibody was raised against a 17 amino acid synthetic peptide near the center of human ZIMP7. The immunogen is located within amino acids 270 - 320 of ZIMP7. |
Cross-reactivity |
At least four isoforms are known to exist. ZIMP7 antibody is predicted to not cross-react with other PIAS protein family members. |
Purification |
ZIMP7 Antibody is affinity chromatography purified via peptide column. |
Storage |
ZIMP7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Gene Full Name |
Zinc finger, MIZ-type containing 2 |
Molecular Weight |
96537 MW |
Protein Function |
Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors. |
Subcellular Localization |
Nucleus |
Tissue Specificity |
Expressed most abundantly in testis with lower levels in heart, brain, pancreas, prostate and ovary. |
Protein Name |
Zinc finger, MIZ-type containing 2 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.