Anti-ZIMP7 ZMIZ2 Antibody

Primary Antibodies

Boster Bio Anti-ZIMP7 ZMIZ2 Antibody (Catalog # A09987). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.

Polyclonal

ZIMP7 Antibody is supplied in PBS containing 0.02% sodium azide.

ZIMP7 antibody was raised against a 17 amino acid synthetic peptide near the center of human ZIMP7. The immunogen is located within amino acids 270 - 320 of ZIMP7.

ZIMP7 Antibody is affinity chromatography purified via peptide column.

Zinc finger, MIZ-type containing 2

Increases ligand-dependent transcriptional activity of
AR and other nuclear hormone receptors.

Expressed most abundantly in testis with lower
levels in heart, brain, pancreas, prostate and ovary.