Anti-WDR35 Antibody

Primary Antibodies

Boster Bio Anti-WDR35 Antibody (Catalog # A07256). Tested in ELISA, IHC-P applications. This antibody reacts with Human.

WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription. One such protein, WDR35, also known as CED2, has been shown to be mutated in patients with Sensenbrenner syndrome/cranioectodermal dysplasia (CED), an autosomal-recessive disease that is characterized by craniosynstosis and ectodermal and skeletal abnormalities. WDR35 localizes to cilia and dentrosomes during embryogenesis and human and mouse fibroblasts that lack this gene fail to produce cilia. Mutations in this gene can also cause short-rib polydactyly syndromes due to abnormal ciliogenesis.

Polyclonal

WDR35 Antibody is supplied in PBS containing 0.02% sodium azide.

WDR35 antibody can be used for detection of WDR35 by immunohistochemistry at 5 μg/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

WDR35 antibody is human specific.

WDR35 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

133547 MW

Cytoplasm, cytoskeleton, microtubule
organizing center, centrosome. Cytoplasm,
cytoskeleton, cilium axoneme. Cytoplasm,
cytoskeleton, cilium basal body.