Anti-FEZ1 Antibody

Primary Antibodies

Boster Bio Anti-FEZ1 Antibody (Catalog # A04986). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Similar to its C. elegans homolog UNC-76, mammalian FEZ1, an abundant membrane protein and protein kinase C (PKC)-Z substrate, is involved in axonal guidance. Following phosphorylation by PKC-Z, FEZ1 translocates from the plasma membrane to the cytoplasm. FEZ1 is then able to interact with a number of proteins involved in axonal outgrowth and cellular transport such as DISC1, a candidate gene for schizophrenia, as well as kinesin-1, a microtubule-based motor protein. FEZ1 also interacts with proteins involved in transcriptional regulation and chromatin remodeling, suggesting that FEZ1 may have nuclear regulatory functions in addition to those for neuronal development. At least two distinct isoforms of FEZ1 are known to exist.

Polyclonal

FEZ1 Antibody is supplied in PBS containing 0.02% sodium azide.

FEZ1 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human FEZ1. The immunogen is located within amino acids 270 - 320 of FEZ1.

FEZ1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

45119 MW

Cytoplasm, cytoskeleton, microtubule
organizing center, centrosome

Fasciculation and elongation protein zeta 1 (zygin I)