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Anti-RILP Antibody

Anti-RILP Antibody

Item no.	BOS-A03940
Manufacturer	Boster
Amount	0.1mg
Format	Liquid
Applications	WB, IF, ICC, ELISA
Specific against	Human, Mouse
Host	Rabbit
Isotype	IgG
Alias	PP10141, Rab-interacting lysosomal protein
Available
Manufacturers Product Category	Primary Antibodies
Manufacturers Research Category	Homeostasis
Short Description	Boster Bio Anti-RILP Antibody (Catalog # A03940). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.
Description	Boster Bio Anti-RILP Antibody (Catalog # A03940). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.
Background	The Rab interacting lysosomal protein (RILP) is lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. It is thought that RILP is a downstream effector of RAB7 and both proteins act together in the regulation of late endocytic traffic. Overexpression of RILP caused enlarged lysosomes that are more centrally located in the cell suggesting that RILP may also be involved in the regulation of lysosomal morphology. Other evidence suggests that RILP may play a role in the biogenesis of multivesicular bodies.
Gene Name	RILP
Clonality	Polyclonal
Concentration	1 mg/mL
Contents	RILP Antibody is supplied in PBS containing 0.02% sodium azide.
Application Details	RILP antibody can be used for detection of RILP by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 2.5 μg/mL. Antibody validated: Western Blot in mouse samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Immunogen	RILP antibody was raised against an 18 amino acid synthetic peptide near the center of human RILP. The immunogen is located within amino acids 110 - 160 of RILP.
Purification	RILP Antibody is affinity chromatography purified via peptide column.
Storage	RILP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Gene Full Name	Rab interacting lysosomal protein
Molecular Weight	44200 MW
Protein Function	Rab effector playing a role in late endocytic transport to degradative compartments. Involved in the regulation of lysosomal morphology and distribution. Induces recruitment of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments. Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes.
Subcellular Localization	Late endosome membrane
Protein Name	Rab interacting lysosomal protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1mg

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Delivery expected until 10/4/2024

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